Abstract:Biotechnology research and development has become an important area of intellectual property, as the rapid development of knowledge economy and biotechnology. Due to the long development cycle, too many approval links, and related intellectual property rights, the cultivation of target varieties and the development of biotechnology industry put forward higher requirements on institutional innovation to promote information sharing, knowledge flow and technology transfer.Based on pursuing the rational spirit of intellectual property public policy and learning the rational design on the evolution of intellectual property policies of major developed countries, this study analyzed the rational appeal and explored the choice of public policies of Chinese biotechnology intellectual property, which will bring new inspiration to improve the efficiency of biotechnology R D investment and the level of IP operation management.