Abstract:As a key indicator of sustainable development, ecological efficiency runs through the whole process of innovation and industry development. Relevant data of the Yangtze River delta from 2009 to 2018 were selected on the article and uses the coupling coordinated degree model to measure, compare and analyze the spatial-temporal evolution of the coupling coordinated degree of regional synergic innovation, industrial structure, and ecological efficiency. The results show that the coupling degree and coupling coordination degree of the three subsystems in the Yangtze River Delta are ups and downs with the evolution of time series, and the stage is obvious, but the spatial differentiation is more noticeable, showing the law of decreasing from Shanghai to the periphery. According to the coordinated development of subsystems in different regions of the Yangtze River Delta, it can be divided into four development modes: high-coordinated development of the system, synergic innovation lagged, industrial structure lagged, and ecological efficiency lagged. At the same time, the imbalance between ecological efficiency and synergic innovation and industrial structure severely restricts the coordinated development of the ternary system. Finally,the pertinence suggestions are put forward respectively.