Abstract:This paper uses PP model to deal with the feature of dimensionality reduction of high-dimensional data, the problems existing in measuring the inputs and outputs efficiency of science and technology finance by SFA method were solved. On this basis, the empirical study on the provincial panel data of China""s sci-tech finance input and output from 2010 to 2017 shows that there are differences in the mean values of sci-tech finance efficiency in the eastern, central and western regions, and uneven development of sci-tech finance in each province. The inputs of local government and financial institutions in science and technology finance is promoting the efficiency of science and technology finance in China. The total number of R&D personnel is a favorable factor to promote the efficiency of technology and finance. According to the empirical results, the paper puts forward corresponding suggestions.