Abstract:In order to explore the establishment of more efficient campus entrepreneurial environments and improve the survival rate of start-ups, an empirical study is made on the mechanism of the impact of universities’ creating space environment on the performance of start-ups in China. An empirical investigation of a total of 417 sample data of start-ups in 32 colleges and universities in Shandong, Zhejiang and Guangdong found that: Entrepreneurial environment of universities’ creating Space have significantly positive effect on the ability to integrate resources of start-ups, universities’ creating Space have significantly positive effect on Performance of start-ups, The ability to integrate resources have significantly positive effect on Performance of start-ups, The ability to integrate resources plays a mediating role between entrepreneurial environment of universities’ creating space and Performance of start-ups.