区域一体化是经济发展必由之路，产学研结合是实体经济走出困局的必然选择。大科学装置在区域科技和经济一体化发展中扮演着日益重要的角色。选取长三角作为典型地区分析大科学装置优化布局和共建共享的思路，引出装置对区域一体化影响的数学化研究，通过经济建模探讨经济发展和学科交叉的困局与出路，进而利用模型推导演绎大科学装置共建共享和分类应用产生的社会经济价值。基于研究发现，提出如下政策建议：大科学装置应加强分类避免重复化建设，建立和完善共建、共管、共享的体制机制，实现区域科技和经济一体化联动发展及协同创新需要不断激发政府、企业、高校及科研院所等非同类运行主体的活力，最终形成有效合力。

Integration of international economics and structural change of economic growth have made regional integration a general tarend of events. The combination of production, study and research will help the economy out of the current dilemma greatly. Large-scale scientific facilities play an important role in the development of regional science and technology and economic integration. This article analyzes the optimization layout and co-construction and Sharing ideas of large-scale scientific facilities in the Yangtze River Delta region by mathematical derivation, explores the dilemma and outlets of economic development and interdisciplinary interaction through economic modeling, uses the model to promote the social-economic value for joint development and classified application of the large-scale scientific facilities.Based on the research findings, the following policy recommendations are proposed: large-scale scientific facilities should strengthen classification to avoid duplication of construction, establish and improve the institutional mechanisms of co-construction, co-management and sharing, and realize the coordinated development of regional science and technology and economic integration and collaborative innovation needs to continuously stimulate the operation of government, enterprises, universities and research institutes. Finally, effective resultant force is formed.

F207

国家自然科学基金项目（面上项目，重点项目，重大项目）