Abstract:Since the main body of basic research is colleges and universities, scientific and technological innovation in colleges and universities is not only an important guarantee for building an innovative country, but also the key to achieve industrial upgrading and economic transformation. At this stage, it is urgent to improve the efficiency of scientific and technological innovation in colleges and universities under the limited investment of university resources. This paper divides the scientific and technological innovation in colleges and universities into knowledge innovation stage, scientific research innovation stage and innovation income stage from the perspective of innovation value chain, analyses the efficiency of scientific and technological innovation in 30 provinces and municipalities in China from 2005 to 2017 by using the Super-SBM, and analyses the dynamic trend of efficiency evolution in the three stages by taking the north comprehensive economic zone, the middle yellow river comprehensive economic zone and the whole China as an example. This paper finds that: (1) not only the efficiency at all stages and overall efficiency of scientific and technological innovation in China"s colleges and universities are relatively low, but also the gap between provinces with high innovation efficiency and provinces with low efficiency is widening; (2) there are situations of knowledge innovation efficiency > scientific research innovation efficiency > innovation income efficiency in all stages; (3) there are obvious stages and differences in the efficiency of scientific and technological innovation among universities in different regions. Among them, the comprehensive economic zones such as the middle reaches of the Yellow River, the eastern coast and the middle reaches of the Yangtze River have higher efficiency in the stage of knowledge innovation, while the comprehensive economic zones such as the eastern coast, the southern coast and the northern coast have higher efficiency in the stage of scientific and technological innovation, and the comprehensive economic zones such as the southern coast and the northern coast have higher efficiency in the stage of innovation income. This paper puts forward countermeasures and suggestions on the shortcomings of colleges and universities in the process of scientific and technological innovation at the present stage.