Abstract:The paper evaluates the efficiency of S T innovation in Qinghai Province from 2000 to 2017 from both static and dynamic perspectives using the CCR model based on DEA and Malmquist productivity index. The results show that: from the perspective of static efficiency, the comprehensive efficiency and scale efficiency of S T innovation are low, the pure technical efficiency is relatively effective, and the scale efficiency is in the state of increasing scale; from the perspective of dynamic efficiency, the slow progress of technology and the improvement of technical efficiency do not significantly drag down the growth of total factor productivity; during the investigation period, the efficiency of S T innovation shows "rise decline rise" ”However, the efficiency of S T innovation is generally low, which is at the downstream level in the five northwest provinces, which is related to the economic development history, economic development level, industrial development demand, scientific and technological investment management and scientific and technological innovation system of Qinghai Province.