Abstract:scientific and technological resources are the material and information resources needed for scientific and technological activities, and are the basic conditions for improving the collaborative innovation ability of enterprises. The sharing of scientific and technological resources can improve the utilization efficiency of scientific and technological resources. In this paper, the framework of demand, content and method system of science and technology resources is established, including: (1) demand system of science and technology resources sharing, which is mainly premium end, personalized, green and humanized demand. (2) The content system of scientific and technological resources mainly includes knowledge, data, products, talents, software, hardware and other scientific and technological resources. (3) The method system of science and technology resources sharing analyzes the content and relationship of the methods of description, integration, evaluation and sharing of science and technology resources. Science and technology resources sharing is a system engineering, which needs to describe, integrate and evaluate the science and technology resources, and then share the science and technology resources. The research significance of this paper is: (1) a comprehensive study of the content, sharing needs and sharing methods of scientific and technological resources will contribute to the top-level design of the standard system and information platform for open sharing of scientific and technological resources. (2) Research and Practice on the description, integration, evaluation and sharing of scientific and technological resources as a highly related system will help to solve the problem of the sharing of scientific and technological resources.