Abstract:: High Quality Development of manufacturing industry is one of the important measures of supply-side structural reform,the research shows that the advanced manufacturing industry is an important link to promote the high-quality development of manufacturing industry. Entropy weight, value chain height and structural goodness are used to construct the model of China"s advanced manufacturing industry, and the development level of China"s regional advanced manufacturing industry is empirically analyzed. It is found that there are some problems in the development of advanced manufacturing, such as low value chain, poor industrial structure in provinces, and obvious difference in advanced manufacturing level between regions. Based on IE method and value chain view, design the path of industrial engineering for high quality development of Chinese manufacturing industry: increasing innovation input to realize the high-end value chain, opening up the development and opening up of the manufacturing industry, expanding domestic demand and promoting the optimization of the provincial manufacturing structure.