Abstract:This paper used the provincial panel data of agricultural research institutes from 1999-2017,DEA Malmquist index was used to calculate agricultural total factor productivity,the resource mismatch model established by Hsieh and klenow was used to calculate the total mismatch index of agricultural science and technology resources.A threshold model based on the mismatch of regional agricultural science and technology resources was established to empirically ananlyse the nonlinear mechanism of mismatching agricultural science and technology resources. empirical results shows that:frist,agricultural science and technology resources are misallocated to different degrees in 25 provinces of china,the mismatch of agricultural scientific and technological resources has been improved but the effect is not obvious.second,there is an obvious double threshold effect between agricultural science and technology resources mismatch degree and agricultural total factor productivity,and the change of agricultural total factor productivity is significantly limited by the regional agricultural science and technology resources mismatch degree.third,there is a U-shaped relationship between agricultural science and technology mismatch and agricultural total factor productivity has different influence.