Abstract:By discussing regional scientific and technological innovation and the ecological environment optimization of coupling coordination mechanism, construct the comprehensive evaluation index system, using the coupled coordination degree model, exploratory spatial data analysis and spatial econometric model, making an analysis on the coupling and coordination development degree, spatial and temporal pattern and driving factors of scientific and technological innovation and ecological environment optimization in 30 provinces from 2008 to 2017. The results show that the level of scientific and technological innovation and ecological environment optimization, as well as the coupling and coordination degree of both provinces and regions show a trend of fluctuation, and the gap between regions is expanding. The mean coupling coordination degree of the two systems in each province is between 0.299 and 0.654. On the whole, the spatial pattern of "east high, middle level and west low" and the spatial correlation of "high - low" cluster are shown. Factors such as ecological level of industrial structure, degree of market competition, government support for scientific and technological innovation, environmental regulation, and regional urbanization rate all have significant positive effects and spatial spillover effects on the coupling coordination degree of the two provincial systems in China, and show obvious characteristics of regional heterogeneity. Therefore, based on the heterogeneous influence of these drivers, a differentiation policy proposal is put forward to promote the coupling and coordinated development of two regional systems.