Abstract:Infectious diseases, terrorist attacks, wars, and many threats in the field of biosafety make the improvement of national biosafety governance capability imminent. In the background of novel coronavirus pneumonia pandemic, we start from the international comparison perspective, and sort out the history of biosafety development in the United States, Britain and Australia. Then we analyze and explain the strategies, directives and legislations issued in the process of development. Combined with the problems exposed by China in the process of prevention and control of novel coronavirus pneumonia pandemic, drawing lessons from the three countries. We put forward the measures to improve the legal system of biosafety, accelerate the construction of biosafety strategy and establish the Central Biosafety Defense Committee, to provide useful reference for China to build a national biosafety prevention and control system high efficiently and improve the national biosafety governance capability.