Abstract:The novel corona virus is a serious impact on the global economy. Insisting on innovation driven development strategy is the inevitable requirement for China to restore economy and achieve high quality development. Based on the analysis of the theoretical connotation, function, growth path and construction focus of the international science and technology innovation center, this study studies Germany's construction of European and even global science and technology innovation from five aspects: Science and technology development strategy, support for cutting-edge technology research, financial support system of science and technology innovation, direct promotion of enterprises' innovation and creation, and help high-tech enterprises improve international management. It also explains its enlightenment to the construction of the international science and technology innovation center in Guangdong, Hong Kong and Macao, that is, to formulate the planning of the international science and technology innovation center in Guangdong, Hong Kong and Macao, to avoid self governance; to adhere to the equal emphasis on basic research and Application Research, to provide long-term power for the science and technology innovation center; to build the international science and technology innovation platform as the starting point, to improve the efficiency of collaborative innovation; to increase the support of the government in science and technology finance We should hold and avoid excessive marketization, and build an international industrial science and technology innovation center focusing on improving the quality of the real economy. It will provide some reference for the construction of international science and technology innovation center in Guangdong, Hong Kong and Macao.