Abstract:Digital transformation and innovation have enabled various industries to integrate with each other, and the industrial boundary has shrunk and disappeared, which can bring new opportunities for industrial integration and development.Using 31 provincial economic spatial panel data from 2011 to 2018, transforming labor innovation investment from digital transformation, digital transformation capital innovation breakthrough, digital innovation platform investment and digital innovation environment investment, etc. Multi-dimensional, using Matlab2012b software to construct a spatial econometric model of the spatial spillover effect of digital transformation innovation on industrial integration.It was found that : (1) There is a low overall industry integration in our country and also the industrial integration has strong regional differences. (2) Labor innovation investment, capital innovation investment, innovation platform investment, and innovation environment investment are the main influencing factors of industrial integration. (3) Environmental innovation investment has a “shadow effect” and capital innovation investment has a “standard effect”. In the end, the policy recommendations were made for the research results.