Abstract:The paper studied cooperative patent network of antiviral drugs for COVID-19 in China with the context of epidemic situation. It would enhance the cooperation of antiviral agents in China and expand the recognition of R D knowledge flow and innovation rules of Chinese antiviral agents. It studied the overall structure, individual structure, drug dimension and cooperation between provinces and cities, based on the database of "COVID-19 patent information platform" of Jiangsu information center. The main findings are as follows: (1) The scale, cooperation and cooperation frequency of COVID-19 related antiviral drug cooperation network have been increasing, but the density of cooperation has been decreasing. The trend shows that there is still a large space for cooperation among innovation subjects in this field; (2) Most of the key nodes such as universities, research institutions or enterprises, have great variation in patent cooperation network, which shows that there are difficulties to establish long-term and stable cooperation relationship among innovation subjects; (3) The patent cooperation network scale and network density of antiviral drugs have changed differently, which depends on the characteristics of the diseases; (4) From the perspective of cooperation center between provinces and cities in China, there is an evolving tendency from Beijing to the cooperation among the core provinces and cities in the Delta and the Pearl River Delta.