Abstract:Under the "One Belt And One Road" framework, it is very necessary to accelerate scientific and technological cooperation between China and central and eastern European countries. This paper USES the Innovation Composite Index and the Global Innovation Index to analyze and study the scientific and technological innovation capacity of China and CEE countries. Using a large amount of data analysis between China and central and eastern European countries to input and output of science and technology, through the comparison for China - central and eastern Europe the level of science and technology development, provide the basis for the development of science and technology cooperation, and puts forward specific Suggestions on strengthening technology cooperation between China and central and eastern Europe, in order to further promote regional scientific and technological cooperation and achieve common development goals for the "area" to provide theoretical guidance.