Abstract:Using entropy weight method and coupling coordination model, this paper calculates the comprehensive score and coupling coordination degree of the nine cities in the Pearl River Delta from 2008 to 2018, and discusses the coupling coordination status and distribution characteristics of the three systems from the perspective of time series. The results show that: in the past 11 years, the coupling coordination of ecology, economy, science and technology innovation of the nine cities in the Pearl River Delta is relatively stable, showing the spatial characteristics of "high in the middle, low around"; from the coordinated development and lag type, the cities on the verge of maladjustment and decline often belong to the ecological lag type, while the cities on moderate or mild maladjustment and decline often belong to the scientific lag type The bottleneck of breaking through the maladjustment is different in different cities. In the future, it is necessary to realize deep-seated linkage and cooperation among ecology, economy and science and technology, so as to promote the coordinated development of ecological economy in innovation regions.