Abstract:The United States is a technological innovation superpower. Recently, in order to maintain its leading position in the world"s science and technology, the United States has constantly adjusted its science and technology innovation strategy and introduced relevant science and technology policies. The new trend of science and technology innovation policy in the United States deserves our study and close attention. Based on the analysis of the recent strengthening of the "entity list" in the United States hindering China"s scientific and technological innovation, this paper focuses on the impact of the new trend of American science and technology innovation policy on China and the new opportunities of China in the current situation. Compared with the specific practice of the United States, this paper puts forward six suggestions, such as clarifying the impact of the "entity list" on China"s main economic battlefield and scientific and technological innovation, improving the collaborative technology research and development system of civil military integration in view of China"s major needs, and improving the national system for tackling key core technologies.