Abstract:By means of public data retrieval, data analysis and statistics, industry report analysis and industrial policy interpretation, this paper reviews and summarizes the innovation and development status and achievements of scientific instrument industry in the Guangdong-Hong Kong-Macao Greater Bay Area in recent 10 years.The results show that the market demand for scientific instruments in the region is strong, the related enterprises are mainly located in Guangzhou, Zhongshan, Shenzhen and Dongguan, the overall scale of enterprises is small but developing rapidly and initially forming a gathering trend, a series of large scientific equipment have been or will be built, and the manufacturing of high-end scientific instruments such as gene sequencers and mass spectrometers has been in the leading position in China. However, there are still some problems, such as weak R & D capability, serious homogeneity of industry, lack of high-end instrument R & D personnel and so on. Accordingly, the strategy on future development of scientific instrument industry in Guangdong-Hong Kong Kong-Macao Greater Bay Area is suggested from the aspects of encouraging basic theoretical research and original innovation, focusing on the layout of key strategic emerging industries, strengthening cooperation among Guangdong, Hong Kong and Macao, collaborative innovation of production, education and research, and improving talent cultivation mechanism and related platform construction.