Abstract:In order to promote the Guangdong-Hong Kong-Macao Greater Bay Area to strengthen basic research and the original innovation capabilities, this paper puts forward a basic research policy analysis framework including basic research investment, talents, colleges and universities, and scientific research infrastructure, on this basis, to study and the policy experience of the United States, the European Union, Japan, Singapore and other scientific and technological innovation powers to strengthen basic research, combined with the current situation and existing problems of basic research in the Guangdong-Hong Kong-Macao Greater Bay Area, this paper puts forward seven suggestions to strengthen basic research, including the continuous increase in basic research funding, accelerate the construction of major scientific and technological infrastructure, explore a more flexible and efficient laboratory management and operation mechanism, unite Hong Kong and Macao forces to carry out basic research, accelerate the creation of a world-class research university, explore the implementation of the Nobel Prize Zero Breakthrough Plan in the Greater Bay Area, formulate the "Return Plan for Chinese Scientists" and explore the implementation of the skilled migration system.