Abstract:The paper attempts to clarify whether the impact of Chinese enterprises' trade on their innovation performance is really developing towards the domestic and international markets. Using World Input-Output Database, China Industry Business Performance Database, China Customs Data, Chinese enterprise patent data and "China Urban Statistical Yearbook" data, the relevant information of industrial enterprises and regions from 2000 to 2007 was obtained. Taking the enterprise's export upstream degree, import upstream degree and net upstream degree as the core explanatory variables, the position of Chinese enterprises' participation in the division of labor in the domestic and international markets is calculated. Through regression analysis on the degree of participation in the global value chain and enterprise innovation, it is found that enterprises return to their own countries by importing intermediate goods for pure domestic production. Production helps to improve innovation capabilities, and at the same time, the increase in the number of domestic production links promotes enterprises to carry out innovative behaviors, especially for private enterprises, participating in domestic production can make up for their disadvantages in international trade; Furthermore, it is proposed that the macroeconomic environment has an effect on the above effects. In addition to the role of the government's macro-guidance, the regulatory role of "strengthening the positive and weakening the negative", enterprises themselves can influence the material and human conditions of innovation through the introduction of foreign capital and the attraction of high-tech talents, thereby enhancing innovation capabilities.