Abstract:To monitor the achievements and shortcomings of Guangdong’s innovation-oriented province construction scientifically and effectively, this paper adopts a comprehensive weighted evaluation method to construct Guangdong's innovation capability monitoring index system from innovation environment, innovation input, innovation output, enterprise innovation, and innovation performance five aspects, which draws on the research results of innovation monitoring at home and abroad, and based on the new stage of Guangdong's technological innovation.The monitoring results show that Guangdong's technological innovation capabilities have been greatly improved during the "13th Five-Year Plan" period with fruitful innovation output, this is because that the innovation environment has been continuously optimized, the innovation atmosphere has become stronger, and innovation investment has increased significantly. As the status of enterprise innovation as the mainstay has been continuously consolidated, there are still some problems, such as that a foundation Research funding is relatively low, the conversion rate of enterprise innovation output results is low, and innovation is insufficient to promote green development, including forming a stable investment mechanism for basic research, encouraging large-scale leading enterprises to carry out basic research, taking the Guangdong-Hong Kong-Macao Greater Bay Area and Shenzhen Pilot Demonstration Zones as an opportunity to solidly promote science and technology innovation provincial construction, which can speed up the construction of innovative scientific and technological talents, and continue to deepen the reform of the scientific and technological system