Abstract:Science and technology innovation plays a key role in leading the high-quality development of hospitals.In the process of upgrading to be a hospital with strong strength in science and technology innovation, biobank serve as an important department in supporting the clinical medical research of the hospital. At present, the research on biobanks of hospital is mostly limited to the “Standardization construction”, and the research on the operation and management of the biobank economy is very few. There are four “Bottlenecks”in the sustainable development in biobanks of hospital. This paper focuses on the economic operation and management of biobanks, actively “Invigorate”the existing stocks, and improve the “Sample utilization ratio”, in order to provide decision-making reference for the realization of self-sufficiency and sustainable development of biobanks.