Abstract:To further reveal the digital differentiation mechanism, this paper adopts a fuzzy set qualitative comparative analysis method based on the Technology-Organization-Environment (TOE) framework and combines the prerequisites of regional digital development with 31 Chinese provinces to analyze the driving mechanism behind the digital development of each province, and then derives a grouping path to promote regional digital development. It is found that the level of regional marketization is the single necessary condition affecting the development of regional digitalization; The four driving paths of high regional digital development level are environment-led, organization-environment, balanced and organization-led, mostly with financial resource supply and technology market development level as the core factors; Regional digital quality development requires multiple condition variables to play a synergistic role, and it is difficult for a single or few variables to have an impact on development performance; Potential substitution relationships exist for all condition variables between the groups. Lastly, based on the findings of the study, we put forward countermeasure suggestions such as playing the basic role of financial resources supply and improving the construction of technology trading market system.