Abstract:American basic research has always been in a leading position. Accurately grasping the new trend of American basic research policy is helpful to provide useful reference for China"s basic research policy adjustment and formulation in the new period. By analyzing the new trends of Biden government"s science and technology decision-making mechanism and basic research policy, we find that Biden government has re-examined the policy of "due status of science and technology", which not only greatly improves the status of scientific advisory team, but also expands the science and technology management function of the federal government; Continue to increase investment in basic research, continuously strengthen the application orientation and achievement transformation orientation, and attach great importance to the cultivation of basic research talents. At present, there are still some problems in China"s basic research, such as low investment intensity, insufficient strategic orientation layout, mismatch between supply and demand, restricted talent growth and so on. In this regard, we should actively learn from the useful practices of Biden government, increase the investment scale of basic research funds through multiple channels, improve the strategic demand-oriented basic research management mechanism, strengthen the systematic development view of basic research, and improve the training and management of basic research talent team.