Abstract:At present, the agricultural science and technology cooperation between China and ASEAN countries is still in the initial stage, therefore, this paper discusses the selection mechanism of agricultural science and technology cooperation between China and ASEAN countries to promote the institutionalization level of regional cooperation and enhance the effectiveness of the development strategy, in order to provide reference for promoting the high-quality development of "the Belt and Road" construction. First of all, the economic development of major ASEAN countries is analyzed in multiple dimensions, and the evaluation index system of agricultural science and technology cooperation in the agricultural science and technology cooperation of ASEAN countries is constructed, on this basis, the environmental level of international agricultural science and technology cooperation among major ASEAN countries and the status of agricultural science and technology cooperation are analyzed. Then, the cluster analysis method is adopted to classify major ASEAN countries into five categories, and based on the classification management principle, the main contents and methods for China to strengthen agricultural science and technology cooperation with major ASEAN countries are proposed. The results show that China's agricultural science and technology cooperation with Laos, Myanmar and Cambodia focuses on improving infrastructure level and agricultural productivity, especially agricultural technology innovation based on natural resources; strengthen scientific and technological cooperation with Thailand and Vietnam, especially to improve the digital supply chain level of high-quality rice industry; strengthen cooperation with Indonesia and the Philippines on agricultural digitization and technological innovation, with Malaysia on technology-intensive agriculture, and with Brunei on strengthening scientific and technological exchanges. Finally, it puts forward some countermeasures and suggestions for China to further strengthen agricultural science and technology cooperation with ASEAN countries from the aspects of cultivating characteristic and advantageous economic growth points in the agricultural field, building differentiated cooperation platforms and promoting the construction of information network.