Abstract:The potential ethical risks of the main scientific and technological activities affecting the construction of the Co-prosperity Demonstration Area in Zhejiang Province was explored. Taking "Internet +", life and health and new material Science representative technologies as the research objects, 143 relevant Chinese and English literatures were selected based on Web of Science, PubMed, Scopus, CNKI, Wanfang, VIP and other databases. The problems related to the fairness of information resources, the fairness of biological resources and public safety were sorted out, analyzed and predicted, and the ethical risks of human safety, privacy protection and subject respect were revealed. Based on this, taking the digital integration construction of Zhejiang Province as an example, this paper expounded the practical measures taken by Zhejiang Provincial government as a meta-governor to exercise the third-order governance function, which provided a basic governance platform for the co-governance of multiple subjects, and promoted the participation of multiple subjects in first-order governance, such as the establishment of self-correction and self-examination ethical ecology, ethical governance information platform, etc. It provides a reference for the study of the common ethical risks of emerging science and technology and the exploration of the new mode of scientific and technological ethical governance.