Abstract:The innovation ecosystem is a constantly evolving system. On the basis of putting forward the transformational evolution mode of ecosystem, this study uses the case study method to explore the process mechanism of transformational evolution of mature enterprise innovation ecosystem and the reengineering of competitive advantage. The results show that: External environmental factors and the characteristics of the ecosystem themselves jointly promote the transformative evolution; The evolutionary process is manifested in the formation of a consensus on transformation, promotion of transformational actions and creative subversion, which is mainly driven by the individual forces at the bottom of the system or the strategy of senior leaders; It recreates the differences of internal heterogeneous resource capabilities and external synergistic relations that are suitable for the new industrial environment.