Abstract:Based on the two-stage model of "knowledge creation-knowledge transfer", the two-stage DEA model is used to measure and analyze the overall and phased efficiency of science and technology innovation of universities under the construction of first-class universities during the period from the 12th Five-Year Plan to the 13th Five-Year Plan. The study shows that the overall efficiency of science and technology innovation is not high and the efficiency level varies significantly among universities during the observation period. Compared with the 12th Five-Year Plan period, the efficiency value of the sample universities in the 13th Five-Year period is higher in the knowledge creation stage than in the knowledge transfer stage, but the efficiency value of the knowledge transfer stage increases more than that of the knowledge creation stage. The efficiency development of science and technology innovation sub-stage of different types of universities is uneven, reflecting distinctive orientation and discipline construction characteristics. Combined with the strategic objectives of "scientific and technological self-reliance and self-improvement" and "double first-class" construction, countermeasures and suggestions are put forward to improve the efficiency of scientific and technological innovation in universities from three levels: the state, universities and society.