Abstract:The history of positive interaction between institutional innovation and scientific and technological innovation proves that long-term and systematic scientific and technological legislative reform can lead, construct, ensure and follow up the evolution of scientific and technological innovation paradigm and form ecosystem innovation paradigm. Due to the short history of legislation promoting the evolution of scientific and technological innovation paradigm, the small amount of laws and gaps, the lack of pluralistic symbiosis of scientific and technological innovation subjects, the lack of self-organization and evolution power of innovation system, and the low openness and coordination of innovation environment, China urgently needs to promote the reform of scientific and technological legislation as soon as possible, increase the investment of scientific and technological legislation resources, and promote the diversified symbiosis of innovation subjects and the marketization of scientific and technological innovation through law, Clarify the specific functions of the government in allocating scientific and technological innovation resources, improve the openness and synergy of scientific and technological innovation environment, promote the evolution of China's scientific and technological innovation paradigm to ecosystem innovation paradigm, and lay an institutional foundation for realizing scientific and technological self-reliance and self-improvement.