Abstract:Abstract: Industry, academia, and research show their multiple potentials in the interactive symbiosis. The establishment of an industry-university-research symbiosis in colleges and universities is a strategic choice for the continuous, healthy and rapid development of education, scientific research, and industrial undertakings. The practice and exploration of the Yangtze River Delta Research Institute of NPU shows that the core structure of the industry-university-research symbiosis of first-class universities is: relying on high-tech research and development, based on the development of high-value-added technology products, and focusing on the cultivation of high-growth culture to drive the production of colleges and universities. , the symbiosis of learning, research and other undertakings. The operation of industry-university-research symbiosis is an overlapping process of industry-university symbiosis, academia-research symbiosis, and industry-research symbiosis. Integrated development. The practical path for the construction of industry-university-research symbiosis in first-class universities is to start from the three perspectives of maker space construction, R&D platform construction, and team echelon construction, to promote the internal symbiosis and high-level operation of the industry-university-research symbiosis.