Abstract:The data of scientific research projects in Tibet Autonomous Region in the last 60 years is taken as research object in this paper, the overall situation such as the annual change trend of research project number, distribution pattern of researchfield and subject category, hot topic, undertaking institution and regional distributionof research projects in Tibet Autonomous Region in the last 60 years is reviewed and analyzed. It provides a reference for a comprehensive understanding of the development of scientific and technological undertakings in Tibet, reveals the innovation and development of Tibet driven by science and technology, and puts forward suggestions for promoting the better development of scientific and technological undertakings based on scientific research projects in the Tibet Autonomous Region in the future. The research results show that the investment in research projects in Tibet has increased significantly over the past 60 years, and the project investment is concentrated in the three disciplines of agricultural science, industrial technology and medicine and health, which are closely related to the local industrial layout. Local scientific research institutes, local agencies and universities in Tibet are the main institutions responsible for scientific research projects, and the areas where the projects are undertaken are concentrated in Lhasa. The layout of research projects shows problems such as unbalanced regional allocation, insufficient scientific research motivation of enterprises, and weak external cooperative relations.