Abstract:Improving the governance level of innovation and entrepreneurship ecosystem in colleges and universities has become the core issue to accelerate the training of innovation and entrepreneurship talents. Taking the typical experience of national innovation and entrepreneurship university G University as an example, based on the analysis of qualitative data coding, this paper reveals the overall governance system of university innovation and entrepreneurship education ecosystem. It is found that: (1) university administrators are the leading body of the governance system; (2)ecosystem organizational level and ecosystem environment elements are the key parts of the governance system; (3)according to the difference of governance object and governance background, the governance subject can formulate appropriate governance mechanisms, such as contract mechanism, evaluation mechanism, dislocation development mechanism, interest association mechanism, affective transfer mechanism and so on. The research not only further enriches the ecosystem governance theory of innovation and entrepreneurship in colleges and universities, but also has practical significance for colleges and universities to construct or optimize the ecosystem governance system of innovation and entrepreneurship education.