Abstract:Multidimensional and multi-subject collaborative innovation is the key to the improvement of regional innovation capacity in central and western China. The Interdependent super-network model of regional innovation cooperation is constructed based on the joint invention patent authorization data, and the model is used to analyze the collaborative innovation characteristics such as knowledge diversity, knowledge uniqueness, the spatial radiance of subjects, and bearing degree of urban subjects in Jiangxi Province from 2010 to 2021. The results show that: the development of knowledge by innovation subjects is gradually increasing, and the support of research institutes is insufficient; universities, electric power enterprises, research institutes, pharmaceutical, and medical device companies are the keys to inter-city collaborative innovation, and universities are the core of exploratory innovation in the region; intra-city innovation cooperation is more active, and the frequency of innovation activities outside the same city shows an increasing trend, and operational transportation and chemical metallurgy are the key areas of collaborative innovation in Jiangxi. The key areas are operational transportation and chemical metallurgy. Based on this, relevant policy suggestions are put forward to optimize the structure of the technical knowledge portfolio of regional innovation cooperation, enhance the capability of regional research institutes to attack common technologies, and improve the benign interaction channels between research institutions and enterprises.