Abstract:Artificial intelligence (AI) is changing the research paradigm in the field of biomedicine. In recent years, the United States has formulated a series of policies to promote the application of AI in biomedicine. Therefore, the relevant policies from the United States federal government and departments are analyzed, and the measures taken to promote the application of AI in biomedicine are systematically analyzed from the perspective of policy formulation, organization and management, environmental construction and transdisciplinary cooperation. It is found that the United States federal government carried out strategic traction on the application of AI in biomedicine from multiple levels, such as investment, technology development, data and sharing, resource, ethical and social impact, and the departments related to biomedicine worked hard to build an application bridge between biomedicine and AI in data, tools, talent, funding and regulation. In the process of policy formulation, the United States has fully absorbed various transdisciplinary, diversified and intersectoral views. Moreover, several institutions and advisory committees are set up to promote policy implementation, transdisciplinary cooperation between AI and biomedical research, and to encourage internal and external cooperation partnerships among government, industry, science, medical and research. In addition, the construction of data, tools and environment are also improved to reduce obstacles for biomedical researchers to apply AI. It is suggested that China should accelerate the application of AI in biomedicine from the aspects of policy formulation, organization and management, data and tool construction, shared application environment construction, and transdisciplinary cooperation, to enhance the national strength and seize the opportunity.