Abstract:Taking the comprehensive national science center of the Greater Bay Area as an example, the paper takes the innovation ecosystem as the research object, analyzes the innovation ecosystem of the high-tech zone and the innovation ecosystem of the science city. The structure of the innovation ecosystem of Songshan Lake Science City is discussed. It is found that the Songshan Lake Science City has initially established a scientific and technological innovation system, an innovation industry system, an innovation environment system and an urban function system, and has established a coordination mechanism, a security mechanism and a power mechanism. The innovation ecosystem of Songshan Lake Science City is characterized by systematization of innovation, high-end industry, ecological environment and socialization of functions. On the basis of summing up the construction experience of the three major comprehensive national science centers in China, this paper puts forward countermeasures and suggestions to promote the evolution of Songshan Lake High-tech Zone into the innovation ecosystem of the Science City from the aspects of giving full play to the role of innovation as the source of innovation, strengthening the support and guidance of innovation to industry, paying attention to the creation of the innovation and entrepreneurship ecological environment, and improving the urban function highlighting innovation characteristics.