Abstract:Scientific research is an important driving force for the high-quality development of higher education in western China, and the exploration of scientific research efficiency and influencing factors of universities in western China has far-reaching significance for promoting the coordinated development of education, economy and society.Taking 11 provinces and regions in western China from 2010 to 2019 as the research object, the super-efficiency DEA Window-Malmquist-Tobit model was used to calculate the inter-provincial scientific research efficiency of universities in western China. The results show that the scientific research efficiency in the three major regions is significantly improved in 2019, and the scientific research efficiency in the western regions is higher than that in the central and eastern regions. Compared with 2010, the number of effective areas with comprehensive efficiency and technical efficiency has increased, but the scale efficiency has not reached the effective state. The dynamic efficiency analysis shows that the change of scientific research efficiency in the western region presents a "M" type fluctuation trend, which is obviously affected by the policy. The total factor production efficiency of 9 provinces and regions is greater than 1, and the reduction of scientific research efficiency in universities in Xinjiang and Ningxia is mainly due to the reduced efficiency of technological progress. The influencing factors analysis shows that human resources are in a state of "redundancy", and government support, regional economic structure and population aggregation are significantly positively correlated with scientific research efficiency Therefore, the efficiency of scientific research can be improved by improving the quality of human capital, optimizing the management mechanism of the investment and allocation of scientific research funds, and promoting the development of higher education clusters.