Abstract:The stranglehold technical problem faced by the in vitro diagnosis industry in Guangdong province is caused by both the difficulties that innovative technologies are difficult to overcome, and the problem that the key nodes of the innovation chain are subject to people. Based on the innovation ecosystem theory, this paper defines the connotation of stranglehold technology in the in vitro diagnosis industry, constructs a stranglehold technology identification index system of the in vitro diagnosis industry chain, including the importance of technology, technology safety, technology gap, technology availability, and technology connection barriers, and sorts out and analyzes the causes of stranglehold problems of key raw materials and core components. And from the innovative technology, innovation main body, innovation ecology, innovation management put forward the concrete measures to strengthen the chain and solve the stranglehold problem.