Abstract:Science and technology innovation voucher is a policy tool to promote the cooperation between small and medium-sized technology-based enterprises and scientific research institutes and scientific and technological service institutions, and to promote the sharing of scientific and technological resources. This paper takes Guangdong and Hong Kong science and technology innovation voucher policy as the research object, and uses comparative analysis method to analyze the differences between Guangdong and Hong Kong science and technology innovation voucher from the aspects of funding object, funding service scope, funding method, standard and process, and funding fund management. The results show that : (1) The funding targets of Guangdong Science and Technology Innovation Voucher are more diverse than those of Hong Kong, but the threshold conditions are higher ; (2) The definition of service funded by Guangdong Science and Technology Innovation Voucher is not clear enough compared with Hong Kong ; (3) There are great differences in the funding methods, standards and processes of science and technology innovation vouchers between Guangdong and Hong Kong. (4) Hong Kong Science and Technology Voucher funding management is more standardized than Guangdong, basically covering the whole process of the project. Finally, in order to promote the exchange of science and technology innovation vouchers between Guangdong and Hong Kong, some countermeasures and suggestions are put forward to improve the policy of science and technology innovation vouchers between the two places.