Abstract:In the context of anti-globalization, advancing the growth of specialization and specialization of small and medium-sized enterprises will help China break through the technical bottleneck of "stuck neck" technology. In view of the fact that the existing research has not yet deeply explored the relationship between entrepreneurial risk-taking tendency and the continuous innovation of specialized new small giant enterprises, based on the higher-order theory and management cognition theory, this paper targets at the data of 145 Chinese listed “little giant” companies from 2009 to 2020, and uses the two-way fixed model of controlling enterprises and years to empirically test the mechanism of entrepreneurial risk-taking tendency on the continuous innovation of “little giant” firms and its mediating effect and moderating effect by taking innovation investment and intellectual property protection intensity as mediating variables and moderating variables respectively. At the same time, the heterogeneity of this influence mechanism among different regional environments is tested. The results show that the stronger the risk-taking tendency of entrepreneurs, the better continuous innovation performance of “little giant” firms. This positive promotion effect is more obvious under the background of better external business environment, with innovation investment playing as a complete intermediary role. Entrepreneurs’ risk-taking tendency affects the continuous innovation of enterprises through innovation investment, and the intensity of intellectual property protection negatively regulates the relationship between these two. Based on this, it is suggested that entrepreneurs should dare to take risks, but also improve their ability to identify and prevent innovation risks.