Abstract:The collaborative innovation of "Government-Industry-Academia-Rresearch -Application", as a high-tech innovation incubation model, plays an important role in the development of productivity.In the context of value chain restructuring, the intelligent operational model of this approach is explored. Initially, the interaction mechanisms among collaborative innovation entities are analyzed, followed by an examination of the functional elements and intrinsic collaborative mechanisms that underpin collaborative innovation. Subsequently, the collaborative innovation value chain is restructured from a structural optimization perspective. Lastly, from the perspective of the reconstructed value chain, the intelligent operational model of collaborative innovation is discussed, and implementation recommendations are proposed. It is posited that intelligent technology is key to optimizing collaborative innovation models, necessitating a shift from the traditional value chain structure characterized by single-chain development and comprehensive coordination. Leveraging the collaborative innovation intelligent platform, a star-shaped value chain structure should be established to orchestrate the value activities of innovation entities, optimize resource allocation, enhance innovation efficiency, and maximize both the individual and overall value of innovation entities. Innovation entities should fulfill their distinct roles, bolster government leadership, enhance the innovation environment, intensify talent development, deepen collaboration and application of intelligent technology, and advance the upgrading of collaborative innovation models. This study not only offers theoretical support and practical guidance for the intelligent operation of the collaborative innovation model encompassing "Government-Industry-Academia -Research -Application" but also presents novel perspectives and methodologies for innovation activities within the context of value chain restructuring.