Abstract:The development of the digital economy has fostered the emergence of platform-based enterprises, offering new opportunities for "leapfrogging" technological innovation in China's industries. However, there is a current lack of attention and in-depth research on the mechanisms and influencing factors of cross-border disruptive innovation by platform-based enterprises in the context of digitalization. In light of this, a configurative perspective is used to explore the key factors affecting cross-border disruptive innovation by platform-based enterprises and the impact paths of the combinations of these factors on the success or failure of disruptive innovation. The definition of platform-based enterprises is first provided from a technology management perspective, which is to build a public technology architecture or modular system based on information technology, connect different participants, integrate various resources, provide a variety of products and services, and achieve a business model of multi-party participation and mutual benefit. Subsequently, 32 Chinese listed companies are selected as the research subjects based on the above definition, and public information, annual reports, and patent information from 2017 to 2021 are collected as raw data. A fuzzy-set Qualitative Comparative Analysis (fsQCA) method is used for empirical research. The results indicate: (1) The ability to search for cross-border knowledge is a necessary condition for platform-based enterprises to achieve a high number and quality of cross-border disruptive innovations. (2) The intensity of government subsidies has a relatively minor impact on the number and quality of cross-border disruptive innovations by platform-based enterprises. (3) High cross-border knowledge search ability and broad cooperation are core conditions affecting the quality of cross-border disruptive innovation by platform-based enterprises, while the level of digitization affects the number of cross-border disruptive innovations by platform-based enterprises but has a limited impact on the quality. (4) Digitization helps enterprises discover more opportunities for cross-border disruptive innovation, but improving the quality of cross-border disruptive innovation still requires enhancing the ability to search for cross-border knowledge and extensive cooperation between enterprises.