Abstract:As an important part of the regional innovation system and the national strategic science and technology force, new research and development institutions bear the historical mission of promoting the construction of an innovative country and realizing the self-reliance of high-level science and technology. Finance is the foundation and an important pillar of national governance and plays a vital role in promoting the construction of new research and development institutions. Under this background, the research on the construction of new R D institutions has both theoretical and practical significance. This paper firstly starts from the provincial level of Shandong Province, and focuses on the number, scale, spatial layout, industrial allocation and the current situation of talent resource concentration of new R D institutions in Shandong Province. Secondly, from the perspective of financial support, it analyzes the necessity and policy tools of financial support for the construction of new R D institutions, and points out the existing problems of financial support for the construction of new R D institutions. Finally, it puts forward safeguard measures for accelerating the high-quality development of new R D institutions from the aspects of focusing on the independent development of institutions, emphasizing the investment efficiency, focusing on adhering to the system concept, and gradually improving the supporting measures.