Abstract:Scientific and technological innovation is an important engine to promote the all-round development of economy and society, and scientific and technological innovation ability is an important measure of regional scientific and technological innovation level and competitiveness. From three aspects of investment intensity, platform strength and achievement transformation, this paper compares the gap between Zhejiang and Guangdong and Jiangsu provinces in science and technology innovation ability, and analyzes the reasons for the gap. In order to accelerate the promotion of scientific and technological innovation ability and enable the high-quality development of regional economy and society, it is suggested that Zhejiang should take effective measures from many aspects, such as further stimulating the vitality of scientific and technological innovation talent team, enhancing the power of basic research, enhancing the ability of independent innovation of enterprises, and tapping the potential of open and collaborative research.