Abstract:As scientific goals become more ambitious and the demands of scientific development grow, large-scale scientific facilities have become essential for achieving major breakthroughs across many fields of modern science and technology. These facilities have driven the trend towards open sharing and international cooperation, fostering innovative research and promoting technological advancements. The scientific benefits of large-scale scientific facilities have long been a topic of high importance for the nation. However, related research is relatively limited, and there are still no studies analyzing the impact of the degree of international cooperation on the scientific benefits of these facilities. To address this, this study focuses on large scientific facilities of varying scales and degrees of international collaboration, analyzing their scientific benefits to provide insights for the construction and international cooperation of large scientific facilities in China. The study develops an evaluation index system to assess the scientific benefits of large scientific facilities and applies it to five facilities: the European Synchrotron Radiation Facility (ESRF), DIAMOND, Advanced Photon Source (APS), Linac Coherent Light Source (LCLS), and the National Ignition Facility (NIF) in the USA. These facilities are analyzed through four dimensions: output capacity, funding capability, subject development potential, and international cooperation. Additionally, the study incorporates the dimension of national leadership to assess the scientific benefits at a national level. The findings reveal that while higher levels of multilateral cooperation in large scientific facilities do not always correlate with increased scientific benefits, moderate international collaboration tends to enhance these benefits. Large-scale scientific facilities generally yield higher scientific benefits than smaller ones. Furthermore, the scientific benefits for the host countries of these facilities are typically greater than for other countries, though for facilities with extensive multilateral cooperation, this advantage is less pronounced. Based on these insights, five recommendations are proposed for the development of large scientific facilities in China: (1) enhance support for international collaboration and diversify cooperation models; (2) clearly define the goals of facility construction and prioritize education in fundamental disciplines; (3) foster leadership by China in international cooperation for mutually beneficial outcomes; (4) expedite the development of open and shared platforms for China’s scientific facilities to showcase its scientific and technological strengths;(5) strategically plan the creation of highly integrated international clusters to promote the construction, cooperation, and open sharing of China-led large-scale scientific facilities.