Abstract:The Chinese manufacturing industry now is facing the double embarrassment of “internal independent innovation deficiency” and “external technology monopoly blockade”. A large number of key core technologies are critical missing and the traditional innovation modes does not work in the Chinese manufacturing industry, which calls us to deeply investigate its causes and design novel innovation breakthrough modes. Based on reviewing the existing research on key core technologies, this paper identifies the status quo of key core technologies development of Chinese manufacturing industry with the abroad, finding that the absence status of key core technologies in our manufacturing industry includes two forms. With the help of the analysis of the current situations of the lack of key core technologies, we divide the key core technologies in the manufacturing industry into three types: key generic technologies, cutting-edge technologies and major strategic technologies, and the main causes of absence are the dislocation of the subjects, path dependence, and the misallocation of resources correspondingly. Finally, the paper puts forward specific suitable innovation breakthrough modes for three types of key core technologies in the Chinese manufacturing industry. They are the “Spiral Progressive” mode for key generic technologies breakthroughs, the “Jungle Competition” mode for cutting-edge technologies breakthroughs, and the “Main Layout” mode for major strategic technologies breakthroughs. The conclusions provide references for the Chinese manufacturing industry to make breakthroughs in key core technologies according to the different categories.