Abstract:Science and technology finance is an institutional arrangement that supports the scientific and technological innovation of enterprises throughout their life cycle through financial resources, thereby promoting the formation of scientific and technological innovation industries. According to the differences in the modes of supporting enterprises" science and technology innovation, science and technology finance can be divided into policy-based science and technology finance and commercial science and technology finance, and the two cooperate with each other to achieve a smooth cycle of financing for the whole life cycle of enterprises" science and technology innovation. However, there are real challenges such as confusion between the business models of policy-based and commercial science and technology finance in some areas, structural imbalances, and weakened supply and demand for science and technology finance products. Only by accurately understanding the connotation of science and technology finance, policy-based science and technology finance and commercial science and technology finance, ensuring the security of financing for the whole life cycle of enterprise science and technology innovation, and effectively regulating the potential risks of enterprise science and technology innovation, can we truly guarantee the role of science and technology finance in promoting enterprise science and technology innovation.