Abstract:The digital economy, as a new force of the scientific and technological revolution, provides a new impetus for the enhancement of the toughness of the industrial chain, and in-depth exploration of the impact of the digital economy on the resilience of the intelligent manufacturing industry chain is of great significance to the preservation of the security and stabilization of the industrial chain. In this paper, the impact mechanism of digital economy on the industrial chain resilience of intelligent manufacturing industry was elaborated from four aspects: new elements, new models, new industries, and new formats, and the relationship and mechanism between digital economy and the industrial chain resilience of intelligent manufacturing industry was deeply explored by using China"s provincial panel data from 2011 to 2020. The study reveals that the digital economy can contribute significantly to the resilience of the smart manufacturing industry chain, and the impact on the eastern region and the industry chain with strong profitability is more significant; the results of the mechanism test show that the digital economy can affect the resilience of the smart manufacturing industry chain through promoting industrial innovation and industrial synergistic agglomeration in two ways. Combined with the research conclusions, this paper puts forward policy suggestions for improving the resilience of the industrial chain in the context of digital economy.