Abstract:The Party Central Committee attaches great importance to the reform of the management system of scientific research funds. Several relevant policy documents have been issued to optimize the system and mechanism and innovate ways and methods, continuously improving the allocation and management mechanism of financial science and technology funds. Correspondingly, under the background of the reform of "decentralization, management and service", the decentralization of autonomy and management power also puts higher requirements for research funding management and internal control in colleges and universities, and some new risks and challenges have emerged. By sorting out the policy evolution of the scientific research funds supervision in China since the 18th National Congress of the Communist Party of China, this paper refers to the experience of major developed countries and regions in the use and supervision of scientific research funds, and deeply studies and implements the policy spirit of the Party and the state in deepening the reform of the management system of scientific research funds. This paper tries to promote the improvement of the scientific research funds management system with Chinese characteristics which is suitable for the optimization of the layout of higher education, the improvement of the supporting system, the reform of discipline inspection and supervision system, and the construction of communication platform.