Abstract:Driven by the new round of scientific and technological revolution, Generative Artificial Intelligence(GAI) represented by ChatGPT and Sora is gradually and deeply intervening in humankind knowledge production activities.From the viewpoint of the time subject in the sense of ephemeral, GAI has revolutionized the construction of the new form of humankind knowledge production, changed the subject construction of traditional knowledge production, and made GAI becomes an important power source of knowledge production; enriched the content of knowledge production, promoted the integration of multidisciplinary knowledge and the emergence of cross-disciplinary knowledge; improved the efficiency of knowledge production, and made "Just-In-Time Learning" become a reality.At the same time the wide application of GAI weakens the subjective position of human beings in the production of knowledge, deflates the content of knowledge production, leaving the limits of knowledge production unchecked and so on. In the face of the serious challenges to knowledge production brought about by the rapid development of GAI, it is necessary to reconfigure the layout of the main body of knowledge production in human-machine cooperation, strengthen the governance of the whole process of knowledge production, reexamine the development direction of knowledge production, uphold the concept of technological goodness, and make rational and effective use of this new type of knowledge production tool, so as to provide a new choice for the healthy and sustainable development of humankind knowledge production.